Potential Soybean (Glycine max) (L.) merr) On Histopathology Of Liver And Pancreas In Type 2 Diabetic Mice

Taufiqurrahman, Taufiqurrahman and Christyaningsih, Juliana and Sujono, Sujono (2016) Potential Soybean (Glycine max) (L.) merr) On Histopathology Of Liver And Pancreas In Type 2 Diabetic Mice. Internasional Conference, Health Polytechnic of Surabaya 2016. pp. 517-522. ISSN 978-602-73545-6-2

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Abstract

Background Various diabetic complications caused by poor control of the disease, such as vascular disease systemic (accelerated atherosclerosis), heart disease, microvascular disease of the eye as a cause of blindness and retinal degeneration (diabetic retinopathy), cataracts, kidney damage as a cause of kidney failure and damage to the peripheral nerves (neuropathy diabetic). Method This research was the experimental study and it was randomized pretest posttest control group design. The number of experimental animals in each group were four tails, and total sample were 28 tail, divided into 7 groups . Results The results showed that the average number of cells in the islets of Langerhans of the pancreas third lowest for the group DM mice, while the highest was found in the treatment group DM + extract of soybean variety Wilis, it indicates that the Streptozotocin effective to make the animal into diabetic mice. The percentage of liver cells were dying in preparations painted with Hematoxylin eosin, at least found in diabetic treatment group with the extract of soybean varieties Gema. Conclusion Giving soy extracts on diabetic mice can inhibit damage to the pancreas Langerhans and soy extracts Gema types can minimize the number of liver cell death is lowest. It is advisable to use soybean varieties Gema as an alternative to research on herbal therapy for patients with type 2 diabetes.

Item Type:	Article
Uncontrolled Keywords:	DM, Soybean varieties Gema and Wilis, histopathological liver and pancreas
Subjects:	A General Works > Food and Nutrition A General Works > Food and Nutrition > Nutrition
Divisions:	Poltekkes Kemenkes Surabaya > Pusat Penelitan dan Pengabdian Masyarakat > Penelitian
Depositing User:	Misnawar
Date Deposited:	28 Apr 2023 08:37
Last Modified:	28 Apr 2023 09:19
URI:	http://repo.poltekkesdepkes-sby.ac.id/id/eprint/6825

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