Analysis of Images of Neutrophil Lymphocyte Ratio and Bacteria Density Level of Helicobacter Pylori in Tissue in Gastritis Patients

Rakhmalia, Fadia and Handayati, Anik and Woelansari, Evy Diah and Salleh, Mohd Nazil (2022) Analysis of Images of Neutrophil Lymphocyte Ratio and Bacteria Density Level of Helicobacter Pylori in Tissue in Gastritis Patients. International Journal of Advanced Health Science and Technology, 2 (6). pp. 407-413. ISSN 2808-6422

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Abstract

A chronic inflammatory condition, gastritis can extend for years. The most prevalent cause of gastritis and the primary cause of peptic ulcers, respectively, are infections with Helicobacter pylori. In comparison to non-Helicobacter Pylori gastritis, Helicobacter Pylori infection results in mononuclear (MN) and polymorphonuclear (PMN) cell infiltration and increases the production of proinflammatory cytokines in the stomach mucosa. Histopathological testing for Helicobacter Pylori to make the diagnosis. The aim of this study was to analyze the neutrophil lymphocyte ratio (NLR) in patients with gastritis caused by histological analysis, Helicobacter Pylori was diagnosed. This sort of study was conducted at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya, using descriptive observational research and purposive sampling. The information used includes the outcomes of a biopsy of 60 samples that were identified as having gastritis with histopathological analysis of the identification of Helicobacter pylori bacteria in gastric tissue classified by the level of bacterial density using The Updated Sydney System, as well as haemogram data for complete blood examination to further calculate the neutrophil lymphocyte ratio (NLR). The data were processed using descriptive statistical tests to determine the average neutrophil lymphocyte ratio (NLR). The density of Helicobacter Pylori of the r-Spearman test statistics indicates that (Pν = 0.000) below < 0.005 indicates that there is a strong relationship between the neutrophil lymphocyte ratio (NLR) and the density of Helicobacter Pylori bacteria. The conclusion of this research is the neutrophil lymphocyte ratio (NLR) should be a parameter to check before the invasive treatment to Gastritis patient which is examining the histology of the tissue.

Item Type: Article
Uncontrolled Keywords: Neutrophil lymphocyte ratio (NLR), Helicobacter Pylori bacteria, Gastritis.
Subjects: Q Science > QR Microbiology
Divisions: Poltekkes Kemenkes Surabaya > Jurusan Analis Kesehatan
Depositing User: Misnawar
Date Deposited: 13 Apr 2023 02:01
Last Modified: 13 Apr 2023 02:01
URI: http://repo.poltekkesdepkes-sby.ac.id/id/eprint/6704

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