Evaluation of anti mycobacterial activity of curcuma xanthorrhiza ethanolic extract against mycobacterium tuberculosis h37 rv invitro

Ngadino, Ngadino and Setiawan, Setiawan and Koerniasari, Koerniasari (2018) Evaluation of anti mycobacterial activity of curcuma xanthorrhiza ethanolic extract against mycobacterium tuberculosis h37 rv invitro. Veterinary World, 11 (3). pp. 368-372. ISSN 2231-0916

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Abstract

Aim: The aim of this study was to evaluate the antimycobacterial activity of the Curcuma xanthorrhiza ethanolic extract in vitro. Materials and Methods: Ethanolic extract of C. xanthorrhiza was set by maceration method. The broth microdilution and disc diffusion method were used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC), respectively, of C. xanthorrhiza ethanol extract on strain Mycobacterium tuberculosis H37Rv. Results: C. xanthorrhiza ethanol extract was found to have the antimycobacterial effects with a MIC value of 1600 μg/ml while MBC value of 3200 μg/ml for M. tuberculosis H37Rv. Conclusion: From these findings , it can be concluded that C. xanthorrhiza ethanol extract have an antibacterial activity against Mycobacterium tuberculosis H37Rv in vitro and its potency elevated by increasing the C. xanthorrhiza ethanol extract concentration.

Item Type:	Article
Uncontrolled Keywords:	antimycobacterial, Curcuma xanthorrhiza, minimal bactericidal concentration, minimal inhibitory concentration
Subjects:	G Geography. Anthropology. Recreation > GE Environmental > Environmental Engineering > Environmental Health
Divisions:	Poltekkes Kemenkes Surabaya > Pusat Penelitan dan Pengabdian Masyarakat > Pubikasi
Depositing User:	Nanik Indra Putri Sari
Date Deposited:	01 Dec 2021 03:05
Last Modified:	01 Dec 2021 03:05
URI:	http://repo.poltekkesdepkes-sby.ac.id/id/eprint/3550

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